Nitric Oxide Supplements – Health Benefits, Use, Risks

Scientists have conducted several clinical studies on the effectiveness of nitric oxide supplements, most of which have produced mixed results. In this article, we’ll examine how nitric oxide works in the body and some of the most commonly reported benefits and risks of taking supplementation.

What is nitric oxide?

Nitric oxide is a naturally occurring molecule in your body that causes your blood vessels to widen and trigger the release of certain hormones like human growth hormone and insulin. Nitric oxide supplements are a type of supplement that contains L-arginine and L-citrulline.

Nitric oxide production is vital to overall health because blood, nutrients, and oxygen can travel effectively and efficiently to any part of your body.

How do nitric oxide supplements work?

Nitric oxide supplements can dilate or relax blood vessels. As mentioned earlier, the two most common ones are L-citrulline and L-arginine. L-citrulline is an amino acid (the building blocks of protein) found in nuts, meat, legumes and melons. When sold as a supplement, it can mostly be found packaged as a powder or pill. L-arginine is also an amino acid that occurs naturally in all types of dairy products, red meat, fish, and poultry. As a supplement, it can be bought in the form of a pill, cream, or powder.

A person typically consumes around 5 grams of L-arginine per day through their diet. The body converts the amino acid into nitric oxide, which is then used in various body functions. Scientists believe that nitric oxide relaxes and dilates your blood vessels and improves blood flow to the body.

Many people believe that supplementing with nitric oxide improves blood circulation, which in turn improves performance in various physical activities, improves heart health, promotes healing, and provides the body with many other health benefits. While there are many potential benefits and uses of nitric oxide supplements, in fact, not many studies are done, and the following are the benefits that have been studied.

Health Benefits of Nitric Oxide Supplements

Below is a list of the potential benefits of supplementing with nitric oxide:

Improved heart health

Many studies have found that taking nitric oxide supplements has various heart health benefits. These include reducing blood pressure and stiffness in the arteries, as well as improving blood flow in the carotid artery. It is important to note, however, that scientists conducted these studies on animals, not humans.

Physical performance improvement and recovery

Scientists believe that supplementing with nitric oxide could improve oxygenation to muscles. This could have great potential for improving physical performance and reducing muscle soreness after intense exercise. Studies have also shown that nitric oxide supplementation can improve pain tolerance. However, it has been found that this only applies to people who do not exercise regularly or only moderately. Nor have there been any conclusive results that nitric oxide supplementation can improve the performance of elite athletes. Scientists conducted the studies with young male participants, so they don’t know how this supplement can affect women or the elderly as a whole.

Reduction of er * ctile dysfunction

Because nitric oxide supplements improve blood flow, scientists have conducted studies to see if they can improve blood flow in men with erectile dysfunction. Several studies have shown that nitric oxide supplementation can actually reduce erectile dysfunction in men with mild to moderate symptoms.

Lowering high blood pressure during pregnancy

Preeclampsia is a disorder that occurs during pregnancy and is characterized by high blood pressure. It can be dangerous for both the mother and the baby. A 2005 study found that pregnant women who took L-arginine supplements for long periods of time had lower blood pressure than pregnant women who did not take it. Although scientists need to conduct more studies to get more conclusive results, those so far look promising for women suffering from high blood pressure during pregnancy.

Future studies

The above are some examples of more extensive research examining the effectiveness of nitric oxide supplements. However, no studies have been conducted setting the supplement dose people should take in order to get the same results as the subjects.

Other reported benefits

People can take nitric oxide supplements for a variety of reasons, many of which don’t have any scientific research to back them up. Those who can be expected to have scientific support include:

  • Help with losing weight
  • Improving lung function in people with cystic fibrosis
  • Treating symptoms of altitude sickness
  • Improving recovery after serious injury or trauma
  • Preventing a cold
  • Reducing the side effects of memory loss
  • Healing of foot ulcers from diabetes

However, it should be noted that the majority of these benefits are anecdotal, meaning that people may have reported some benefit, but more research should be done to confirm them.

Possible side effects of nitric oxide additives

If you decide to take a nitric oxide supplement, the first thing to do is to consult your doctor about any medications you are taking and how the supplement may interact with them. For the majority of people, these supplements do not cause any known side effects. When they do occur, they are often not as dangerous and can include:

  • In * rrhea
  • Gas, stomach pain, or heartburn
  • a headache
  • nausea
  • Palpitations

However, some people should not take nitric oxide supplements because of the risk of potentially dangerous side effects. These are people with:

cirrhosis: People with cirrhosis or scarring of the liver should be very careful when taking nitric oxide supplements as this can affect their liver function.

Guanidinoacetate Methyltransferase Deficiency: This is a very rare genetic disorder in which the individual lacks an enzyme that converts arginine to creatine, which is a waste product. Because of this, people with this deficiency shouldn’t take nitric oxide supplements.

Low blood pressure: If the person has low blood pressure, they should not take nitric oxide supplements as there is a risk that it will lower it further. Doctors also recommend that anyone taking these supplements stop before surgery.

Scientists believe there are a few other conditions that nitric oxide supplementation could worsen. These include herpes, kidney disease and after a heart attack. One study found that those who take L-arginine after a heart attack are more likely to die, have another heart attack, and be hospitalized than those who don’t take L-arginine.

It is important to note that this article is not an exhaustive list of all possible situations in which a person should not take nitric oxide supplements. They can interfere with different types of medication, such as: B. against high blood pressure or diabetes. Because of this, it is important that you always consult your doctor when choosing one and make sure it is not interfering with any existing medical conditions or medications you may be taking.


Nitric oxide supplements have been around for decades, but doctors have been reluctant to recommend them because there isn’t enough scientific evidence to support their use for certain health benefits. They prefer to recommend certain lifestyle changes to their patients rather than drugs that scientists have already shown to be effective in treating or curing certain conditions.

These supplements are not known to cause many side effects in most people. Many of them try it out. Again, it is highly recommended that anyone who chooses to take it makes sure there is no illness that could be made worse by nitric oxide. Everyone should consult their doctor first before taking any supplement or any other to ensure that they are making a safe and healthy choice.

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