The Miller School of Medicine at the University of Miami is investigating what effects the COVID-19 vaccines could have on sperm, if any. The study’s lead researcher, Dr. Ranjith Ramasamy, is Associate Professor and Director of Reproductive Urology. “Based on the mechanism by which mRNA works, We don’t expect the COVID-19 vaccines to have any impact on male fertility. But of course we want data to confirm this hypothesis, ”said Dr. Ramasamy. Miller School is recruiting 60 men between the ages of 18 and 50 who would like to receive a COVID vaccine. Study participants receive a semen analysis before vaccination and three and six months afterwards. Daniel Nassau, MD, a Miller School urologist involved in the study, said, “We hope and believe that this study will help confirm the vaccine’s safety in terms of male fertility.” began recruiting on December 14, 2020 when Pfizer was the only COVID vaccine to receive an EUA from the FDA. The approval of the study does not indicate whether vaccinated candidates have since been enrolled by Moderna and J&J or whether the study is limited to Pfizer only.

A similar study, recruiting 75 men between the ages of 18 and 45, is currently enrolled at Sheba Medical Center in Israel. This study began in March 2021 and will include men who either had normal semen analysis prior to vaccination or who achieved spontaneous pregnancy. Candidates will receive a single semen analysis 1-2 months after vaccination with the Pfizer BNT162b2 vaccine. Completion of these two studies will provide the medical community with vital information in support of COVID-19 vaccination, particularly in contrast to concerns about COVID-19 disease and its possible effects on male fertility, which are also still being investigated.

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